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Why Is No One Taking Baby Aspirin for Heart Disease Prevention Anymore?

articleUseronJune 23, 2026

For decades, many older adults popped a baby aspirin daily in an effort to lower their risk of heart attack and heart disease in general. The idea was that baby aspirin makes blood platelets less sticky and would, in theory, stop blockages in the arteries that can lead to heart attack or stroke, explains Kevin Shah, MD, cardiologist and program director of Heart Failure Outreach at MemorialCare Heart & Vascular Institute at Long Beach Medical Center in Long Beach, California.

But more recent scientific data suggests that this actually isn’t the best way to go for everyone. With that, some people have stopped this common practice—make that a lot of people.

Now, new data from electronic health record research company Epic Research found that use of baby aspirin to lower the risk of cardiovascular disease has fallen from 7.2 percent to 3.2 percent (around 57 percent) since 2018. Some people are still taking these—the report found that 5.7 percent of adults aged 80 and up were the biggest users—but this once-common practice has clearly fallen out of favor across the board.

Why is that the case and who might still benefit from this? Cardiologists break it down.

Meet the experts: Jim Liu, MD, a cardiologist at The Ohio State University Wexner Medical Center; Aeshita Dwivedi, MD, cardiologist at Northwell’s Lenox Hill Hospital; Corey Bradley, MD, cardiologist at New York-Presbyterian/Columbia University Irving Medical Center; Kevin Shah, MD, cardiologist and program director of Heart Failure Outreach at MemorialCare Heart & Vascular Institute at Long Beach Medical Center in Long Beach, CA

What did the report find?
For the report, researchers analyzed data from 279 million primary care visits that happened between 2015 and 2025 in adults aged 40 and older. The researchers excluded patients who would have used aspirin for another condition, like coronary artery disease, prior stroke, or peripheral artery disease.

After crunching the data, the researchers discovered that visits where low-dose aspirin appeared on the list of medications a patient took fell from a peak of 7.4 percent in mid-2018 to 3.2 percent by the end of 2025. The decline has been steady since 2018.

What does the guidance say?
The guidance around taking a baby aspirin for the prevention of cardiovascular disease has changed a lot in the past decade.

In 2016, the U.S. Preventive Services Task Force (USPSTF) gave a ‘B’ grade recommendation for adults aged 50 to 59 with at least a 10% 10-year cardiovascular disease risk to take a baby aspirin, provided they weren’t at an increased risk of bleeding.

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